Siam Natural Organics Herbal Health & Beauty Products
The Incredible powers of Authentic Kwao Krua Kao - Pueraria Mirifica
The esteemed Dr. I. Sandford Schwartz gave a presentation on the incredible powers of Pueraria Mirifica in 2007. This rare root grows only in a specific region of Thailand and has been shown to stabilize hormone levels in post-menopausal women that regularly consume this root. Dr. Schwartz made the presentation at the Advanced Detoxification and Gene Based Medicine Conference hosted by Dr. Garry Gordon March 10-11, 2007.
The UK journal Nature was the first to publish consolidated information on PM in 1960. The Thai Ambassador to the Court of St. James supplied the root sample to The National Research Laboratories in London.
There a team led by Dr. James C. Cain built on research published as early as 1940. Their conclusion was that PM was at least a hundred times as rich in oestrogenic estrogenic activity as red clover . Forty years later, it has been calculated to be around 3,000 times the estrogenic activity of soy isoflavones. Yet, as an adaptogen, it does not exhibit a rise in blood or urine estrogen levels.
The first acknowledged human study on breast enhancement was done in 1999 by Professors Kuramoshi (Japanese)and Yuthana (Thai). They tested [certified] PM species on 50 Japanese women, between 20 and 49 years old, with daily does of 100 mg to 600 mgs / day.
Following our current recommended schedule of the 8th day from the stat of the monthly menstrual cycle to the 21st day. Overall, more than 70% in each group demonstrated breast enlargement or firming. It was only after this study, that Chulalongkorn began reporting anecdotal evidence, used to commercialize breast creams sold on the internet.
To date there have been no valid structured tests demonstrating the efficacy of breast creams containing PM. For that matter, creams said to contain PM may actually contain one of the other 12 Pueraria species, or even a combination of a number of species. One, sold in Malaysia, has evidence of containing synthetic hormonal precursors. Despite the fact that they do work, there have been a number of negative reports from users. Synthetic hormonal precursors will do that.
Butea Superba and 13 species of Pueraria growing in Thailand are all called Kwao Krua. Butea (a completely different species) is Red Kwao Krua and Pueraria are called White Kwao Krua. PM is one of the white species family members. Black Kwao Krua is a totally different species and has little to no valid research.
Unlike White Kwao Krua, Black and Red Kwao Krua grow throughout most of South East Asia. PM also grows in a small mountainous area of Burma, extending from Thailand s north.
Otherwise, it s only (99%) grown in Thailand. Pueraria mirifica may constitute a new class of treatment, safe, low toxicity, showing natural Selective Estrogen Receptor Modulators (SERMs) properties, agonist in specific tissues and antagonist in other tissues. We are continuing to research the effect of our PM extract on estrogen and cell receptor sites, in both the breast and ovarian tissues.
Dr Schwartz stated, "We will update you as soon as the work has been completed. Smith Naturals, after 7 years of researching PM, has amassed some 14 Kgs of research, testing and trials on PM. Until their work, the Thai government listed only 8 species of Pueraria being indigenous to Thailand. Currently, they maintain distinct Pueraria 13 species in the National Herbarium".
Miroestrol and its derivatives are known to be approximately 3,000 times more potent than soy isoflavones with respect to estrogen receptor effects. ERb stimulation in the brain has been shown to protect neuronal cells from injury and death from excitotoxins, e.g., MSG. ERb stimulation in the prostate gland helps protect against hyperplasia, and reduce symptoms of benign enlargement of the prostate.
Pueraria mirifica may constitute a new class of safe, non-toxic, effective, hormonal therapeutic support as natural, Selective Estrogen Receptor Modulators (SERMs), with estrogen agonist activity in certain tissues and antagonist activity in others, which help balance hormonal function, and possess significant, anti-aging, protective properties for estrogen sensitive tissues in both men and women. It should be noted that although Miroestrol and Deoxymiroestrol are suggested by the scientific community to the active phyto-chemicals, the industry standard measurement are from other molecular components such as Puerarin, Daidzin, Genistin, & Genistein
Research studies on miroestrol and deoxymiroestrol in Pueraria have demonstrated: strong anti-mutagenic properties anti-carcinogenic effects, esp. among breast cancer and colon cancer lines relatively safe control of perimenopausal and postmenopausal symptoms, i.e., vasomotor instability, hot flashes, night sweats, and mood changeability, similar to effects exhibited by conjugated equine estrogens, but without the toxicity prevention and improvement of osteopenia and osteoporosis in both sexes significant improvement of blood lipid and cholesterol levels enhanced function of the endothelial lining of blood vessels cardiovascular protective properties prevention and reduction of prostate hyperplasia prevention and reduction of erectile dysfunction mammogenic effects, i.e., natural promotion of enlargement, toning and firming of the female breasts, by stimulating healthy, breast gland fibroblastic activity.
Please see the following pages about female hormone balancing;
http://www.siamnatural.com/kwaokruakao.htm [HOW IT WORKS]
http://siamnatural.com/documentation/Siam-Natural_kwao-kreu.htm [benefits and contraindications]
More detailed information on female hormone receptor modulators [SERMs], and DIM Pueraria mirifica far out performs DIM (diindolylmethane) in terms of natural balancing good metabolites called 2-hydroxy estrogens vs. bad metabolites called 4 or 16-hydroxy estrogens.
You can realize the benefits of 100% natural DIM by ingesting fresh vegetables such as broccoli, cabbage, cauliflower and Brussel’s sprouts for increased natural DIM (diindolylmethane). Western doctors generally prescribe pharmaceutical versions of DIM, and that may be what most are taking.
That said, Pueraria mirifica and DIM are 100% fully compatible. [Diindolylmethane, or DIM, is a compound that is formed in your body during the digestion of foods that contain the nutrient indole-3-carbinol.
Indole-3-carbinol is found in cruciferous vegetables such as broccoli, cabbage, cauliflower and Brussels sprouts. Eating these foods, therefore, provides your body with DIM.
Diindolylmethane is also sold in supplemental form and is thought to provide a variety of health-promoting benefits.] Many customers also asked about the ramifications of calcium, vitamin B and folic acid; It's true, these vitamins, minerals and amino acids can significantly contribute to your overall success of Pueraria mirifica on several issues in connection with female hormone receptor modulator balancing, breast firming/enlargement, and better overall nutrition.
According to research this herb contains phytoestrogens that can exert protective hormonal effects similar to estriol. Estriol is known as a very protective estrogen. There is a lack of evidence that estriol would be cancer promoting, but instead is cancer prohibiting. These same protective benefits are not reported with estrone or estradiol, two of the more abundant and potent forms of estrogen in the body.
Pueraria Mirifica attaches to estrogen receptors, making more harmful effects of estrogens ineffective. In fact, according to an article published in 2007 by the Health Sciences Institute stated, “Pueraria Mirifica doesn’t simply mimic estrogen in the body the way that other therapies do, whether bio-identical or not. Instead, the herb (much like the human byproduct it resembles) acts on estrogen receptors. In more clear terms, it acts as a balancing agent: When levels of estrogen are too high, Pueraria Mirifica will tie up receptors to weaken the hormone’s effects – when levels are low, the herb exerts the necessary estrogenic activity without actually increasing the amount of estrogen in your body.
As a result, your hormones are modulated and signs of aging linked to your body’s numerous estrogen-receptors (whether it’s menopausal symptoms, wrinkles, balding, or graying hair) are halted or reversed. And without any risk of toxicity, either”. Current scientific research recognizes that there are two types of estrogen cell surface receptors, the alpha receptor (ERa) and beta receptor (ERb). ERa affects classical, estrogen sensitive tissues, e.g., breasts, uterine endometrium, ovarian stromal cells, male testes and vas deferens, and the hypothalamus in the brain.
Whereas, ERb affects non-classical, estrogen sensitive tissues, e.g., brain, bone, heart, lungs, kidneys, intestinal mucosa, and vascular endothelium in both sexes. Excessive ERa stimulation can lead to breast cancer and other estrogen-dependent cancers. Competitive inhibition of ERa receptors by phytoestrogens, via blocking the binding of the stronger, estrogenic hormones, i.e., estrone and estradiol, can help protect against the development of estrogen-dependent cancers of the breast, uterus, ovaries and prostate.
This is the physiochemical basis for the anti-carcinogenic effect of soy isoflavones, and various other naturally occurring phytoestrogens. Phytoestroegns from various plant sources may either activate or inhibit ERa and/or ERb receptors. Miroestrol and deoxymiroestrol in Pueraria preferentially powerfully stimulate ERb receptors, and inhibit ERa receptors.
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